Artin Soroosh, Ph.D.
Affiliations
Lecturer, Microbiology, Immunology, and Molecular Genetics
Lecturer, Undergraduate Education Initiatives — UCLA Cluster Program
Bio
Artin Soroosh received his Ph.D. in Molecular, Cellular, and Integrative Physiology from UCLA. Prior to that, he earned an M.S. in Medical Physiology from Case Western Reserve University. At the Cleveland Clinic (2012-2016) and UCLA (2016-2021), Dr. Soroosh studied the pathogenesis of Inflammatory Bowel Disease, using cell culture, animal models, and patient tissue to uncover the molecular mechanisms behind Crohn’s Disease and Ulcerative Colitis. After earning his Ph.D. in 2021, he transitioned to a career teaching full-time.
Artin is a lecturer for the Frontiers in Human Aging Cluster course. He also teaches Scientific Analysis and Communication (180A/B) and Introductory Microbiology (101) in MIMG.
Selected Publications
Soroosh A, Fang K, Hoffman JM, Law IKM, Videlock E, Lokhandwala ZA, Zhao JJ, Hamidi S, Padua DM, Frey MR, Pothoulakis C, Rankin CR. Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation. Cell Death Dis. 2021;13(1):8.
Mahurkar-Joshi S, Rankin CR, Videlock EJ, Soroosh A, Verma A, Khandadash A, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p Are Downregulated in Irritable Bowel Syndrome and Are Associated With Barrier Function and MAPK Signaling. Gastroenterology. 2021;160(7):2409-2422.e19.
Soroosh A, Rankin CR, Polytarchou C, Lokhandwala ZA, Patel A, Chang L, Pothoulakis C, Iliopoulos D, Padua DM. miR-24 Is Elevated in Ulcerative Colitis Patients and Regulates Intestinal Epithelial Barrier Function. Am J Pathol. 2019;189(9):1763-1774.
Soroosh A, Koutsioumpa M, Pothoulakis C, Iliopoulos D. Functional role and therapeutic targeting of microRNAs in inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2018;314(2):G256-G262.
Soroosh A, Albeiroti S, West GA, Willard B, Fiocchi C, de la Motte CA. Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments. Cell Mol Gastroenterol Hepatol. 2016;2(3):358-368.e4.