Welcome to the Xing Laboratory of RNA Genomics and Bioinformatics!
Current Research Topics:
The long-term goal of our research is to elucidate how genomic and environmental variation of RNA regulatory networks impacts phenotypic traits and diseases.
We are a hybrid computational and experimental lab. We combine genomic, bioinformatic, molecular, and network approaches to study mRNA processing and
post-transcriptional gene regulation in mammalian cells. We develop novel computational and statistical methods for analysis of massive genome and transcriptome data.
We integrate computational studies with high-throughput and experimental research to systematically investigate
the variation and dynamics of RNA regulatory networks between species, within human populations, and in response to developmental and disease signals.
Sep 2014: We received a 2-year R01 grant from the NIH Roadmap Initiative to study epigenomic control of RNA processing.
Aug 2014: Our work in collaboration with Dr. Yang Shi (Harvard) on a chromatin regulator of intron retention has been accepted for publication by Molecular Cell.
Oct 2013: Our work with Beverly Davidson (University of Iowa) on mapping microRNA binding sites in the human brain will appear in the journal Neuron.
Sep 2013: We received a 5-year NIH R01 grant (R01NS076631) from the National Institute of Neurological Disorders and Stroke (NINDS) to study the transcriptome landscape of Huntington's disease.
Jun 2013: Dr. Yi Xing is appointed as a regular member of the NIH GCAT (Genomics, Computational Biology and Technology) study section (2013-2019).
Jun 2013: We received a one-year research award from the UCLA Broad Stem Cell Research Center (BSCRC).
Feb 2013: Dr. Yi Xing received a 2013 Alfred P. Sloan Research Fellowship. [Sloan Foundation news] [UCLA news]