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Laboratory of Molecular Viral-Host Interactions

Viruses are the best cell biologists. How viruses enter, replicate, and exit their host cells is an evolutionary record of the most successful cell biological strategies that have survived eons of culling by natural selection. We study how viruses co-opt basic cell biological processes to complete their life cycle, and investigate the myriad strategies used by viruses to propagate themselves. By focusing on common threads that underlie viral entry and budding processes, our studies aim not only to enhance our understanding of cell biology on a molecular level, but also reveal targets for therapeutic interventions against a broader spectrum of viral pathogens.